The FibeBiotics Consortium

Goal

• Study the bioactive (health) function of polysaccharides and generate knowledge that support health claims

Hypotheses

• Polysacharides support the gut and immune function
• Innate and adaptive immunity
• Different polysaccharides and formulations can have different bioactivity effects
• Tools & models can help to design functional foods with maintained and standardized proven health effects

Main objectives

• Perform biochemical analysis to study compounds, effect of processing, and structure-function relations
• Develop standardized in vitro screening methods for classification of polysaccharides and support product design
• Use dedicated in vivo and ex vivo analyses to study mechanisms of action and to validate biomarkers
• Use and validate this knowledge in an intervention study based on elderly subjects